| Author(s) | Robert R. Crichton |
 | Year | 2019 |
 | Pages | 670 |
 | Language | English
|
 | Format | PDF |
 | Size | 160 MB
|
 | Publisher | Academic Press |
 | ISBN | 0128117419, 978-0128117415
|
Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Third Edition,
provides a comprehensive discussion of the biochemical aspects of
metals in living systems. The fascinating world of the role of metals in
biology, medicine and the environment has progressed significantly
since the very successful Second Edition of the book published in
2012. Beginning with an overview of metals and selected nonmetals in
biology, the book supports the interdisciplinary nature of this vibrant
area of research by providing an introduction to basic coordination
chemistry for biologists and structural and molecular biology for
chemists.
Having built this accessible foundation, the book
progresses to discuss biological ligands for metal ions, intermediary
metabolism and bioenergetics, and methods to study metals in biological
systems. The book also covers metal assimilation pathways; transport,
storage, and homeostasis of metal ions; sodium and potassium channels
and pumps; magnesium phosphate metabolism and photoreceptors; calcium
and cellular signaling; the catalytic role of several classes of
mononuclear zinc enzymes; the biological chemistry of iron; and copper
chemistry and biochemistry.
In addition, the book discusses
nickel and cobalt enzymes; manganese chemistry and biochemistry;
molybdenum, tungsten, vanadium, and chromium; non-metals in biology;
biomineralization; metals in the brain; metals and neurodegeneration;
metals in medicine and metals as drugs; and metals in the environment.
Now in its Third Edition, this popular and award-winning resource
highlights recent exciting advances and provides a thorough
introduction for both researchers approaching the field from a variety
of backgrounds, as well as advanced students.
- Winner of a 2019 Textbook Excellence Award (Texty) from the Textbook and Academic Authors Association
- Includes a thorough survey of metals in biological systems: in the human body, in medicine and in the environment
- Previous winner (Second Edition) of the 2013 Textbook Excellence Award (Texty) from the Text and Academic Authors Association
- Features
new sections: an overview of the different functions of essential metal
ions; toxic metals in diagnosis and therapeutics; crystal and ligand
field theory and their limitations; molecular orbital theory; genetic
and molecular biological approaches to study metals; more complex
cofactors and their biosynthesis; photosynthetic oxidation of water;
man-made environmental pollution; and metals as poisons
