(Methods in Molecular Biology) 3rd ed. 2016 Edition
by Rajyalakshmi Luthra (Editor), Rajesh Singh (Editor), Keyur Pravinchandra Patel (Editor)
This updated volume explores a wide variety of clinical applications
of PCR such as detecting DNA methylation, detection of viruses and
protozoa in infectious diseases, estimation of gene copy number
aberrations, primer extension coupled with mass spectroscopy, and high
throughput NGS techniques. The application of PCR has shown incredible
value in the study of genomics and transcriptomics, not only for
discovery but also for routine clinical applications, and it forms the
cornerstone of personalized medicine. Written for the highly successful Methods in Molecular Biology
series, chapters include brief introductions to their respective
topics, lists of the necessary materials and reagents, step-by-step,
readily reproducible laboratory protocols, and tips on troubleshooting
and avoiding known pitfalls.
Thorough and authoritative, Clinical Applications of PCR, Third Edition
serves as an ideal guide for researchers aiming to understand the
principles behind each application and for their implementation in the
laboratory.