1st Edition
by Yiyun Cheng (Editor), Donald A. Tomalia (Foreword)
The opportunities and challenges of using dendrimers to improve drug delivery
Among
pharmaceutical and biomedical researchers, the use of dendrimers in
drug delivery systems has attracted increasing interest. In particular,
researchers have noted that the volume of a dendrimer increases when it
has a positive charge. If this property can be applied effectively,
dendrimers have enormous potential in drug delivery systems, directly
supplying medication to targeted human organs.
With contributions
from an international team of pioneers and experts in dendrimer
research, this book provides a comprehensive overview of the latest
research efforts in designing and optimizing dendrimer-based drug
delivery systems. The book analyzes key issues, demonstrating the
critical connections that link fundamental concepts, design, synthesis,
analytical methodology, and biological assessment to the practical use
of dendrimers in drug delivery applications. Topics covered include:
- Dendrimer history
- Synthesis
- Physicochemical properties
- Principles of drug delivery
- Applications in diverse biomedical fields
Dendrimer-Based Drug Delivery Systems
reflects the authors' thorough review and analysis of the current
literature as well as their own firsthand experience in the lab. Readers
will not only discover the current state of the science, but also gain
valuable insights into fruitful directions for future research.
References at the end of each chapter serve as a gateway to the growing
body of literature in the field, enabling readers to explore each
individual topic in greater depth.
Pharmaceutical and biomedical
researchers will find this book a unique and essential guide to the
opportunities, issues, and challenges involved in fully exploiting the
potential of dendrimers to improve drug delivery.