Efficacy Analysis in Clinical Trials an Update: Efficacy Analysis in an Era of Machine Learning
Description
1st ed. 2019 Edition
by Ton J. Cleophas (Author), Aeilko H. Zwinderman (Author)
Machine learning and big data is hot. It is, however, virtually unused in clinical trials. This is so, because randomization is applied to even out multiple variables
Modern medical computer files often involve hundreds of variables like genes and other laboratory values, and computationally intensive methods are required
This is the first publication of clinical trials that have been systematically analyzed with machine learning. In addition, all of the machine learning analyses were tested against traditional analyses. Step by step statistics for self-assessments are included
The authors conclude, that machine learning is often more informative, and provides better sensitivities of testing than traditional analytic methods do
