by Anthropological Survey Of India
ISBNs: 9811601623, 9789811601620, 978-9811601620
English | 2021 | PDF | 22 MB | 460 Pages
This book is the output of Anthropological
Survey of India's National Project "DNA Polymorphism of Contemporary
Indian Population" conducted during 2000 to 2018. The book compiles the
independent and collaborative work of 49 scientific personnel. Genomics
facilitate the study of genetic constitution and diversity at individual
and population levels. Genomic diversity explains susceptibility,
predisposition and prolongation of diseases; personalized medicine and
longevity; prehistoric demographic events, such as population
bottleneck, expansion, admixture and natural selection. This book
highlights the heterogeneous, genetically diverse population of India.
It shows how the central geographic location of India, played a crucial
role in historic and pre-historic human migrations, and in peopling
different continents of the world. The book describes the massive task
undertaken by AnSI to unearth genomic diversity of India populations,
with the use of Uni-parental DNA markers mtDNA (mitochondrial DNA) and Y
–chromosome in 75 communities. The book talks about the 61 maternal and
35 paternal lineages identified through these studies. It brings forth
interesting, hitherto unknown findings such as shared mutations between
certain communities. This volume is a milestone in scientific research
to understand biological diversity of Indian people at genomic level.
It addresses the basic priority to identify different genes underlying
various inborn genetic defects and diseases specific to Indian
populations. This would be highly interesting to population geneticists,
historians, as well as anthropologists.