4th Edition
by David J. Balding (Editor), Ida Moltke (Editor), John Marioni (Editor)
A timely update of a highly popular handbook on statistical genomics
This
new, two-volume edition of a classic text provides a thorough
introduction to statistical genomics, a vital resource for advanced
graduate students, early-career researchers and new entrants to the
field. It introduces new and updated information on developments that
have occurred since the 3rd edition. Widely regarded as the
reference work in the field, it features new chapters focusing on
statistical aspects of data generated by new sequencing technologies,
including sequence-based functional assays. It expands on previous
coverage of the many processes between genotype and phenotype, including
gene expression and epigenetics, as well as metabolomics. It also
examines population genetics and evolutionary models and inference, with
new chapters on the multi-species coalescent, admixture and ancient
DNA, as well as genetic association studies including causal analyses
and variant interpretation.
The Handbook of Statistical Genomics
focuses on explaining the main ideas, analysis methods and algorithms,
citing key recent and historic literature for further details and
references. It also includes a glossary of terms, acronyms and
abbreviations, and features extensive cross-referencing between
chapters, tying the different areas together. With heavy use of
up-to-date examples and references to web-based resources, this
continues to be a must-have reference in a vital area of research.
- Provides much-needed, timely coverage of new developments in this expanding area of study
- Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics
- Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics
- Extensive coverage of human genetic epidemiology, including ethical aspects
- Edited by one of the leading experts in the field along with rising stars as his co-editors
- Chapter authors are world-renowned experts in the field, and newly emerging leaders.
The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.
