1st Edition
by Mario Thevis (Author)
Enables you to detect, identify, and characterize hundreds of drugs that may be used by athletes
Mass
spectrometry has become essential to sports drug testing. This book
examines both the principles of sports drug testing and the use of mass
spectrometry techniques and mass spectral data to detect, identify, and
characterize hundreds of known and unknown drugs that athletes may use
to enhance their performance. The author provides a detailed overview of
the mass spectrometry of numerous classes of therapeutics and agents,
various analyzers to detect low- and high-molecular weight drugs, as
well as techniques to discriminate between endogenously produced and
synthetically derived compounds.
Mass Spectrometry in Sports Drug Testing
begins with a full chapter dedicated to the history of sports drug
testing. Next, the book provides the principles and techniques needed to
maximize the specificity and sensitivity of mass spectrometric assays,
including:
- Detailed, step-by-step assays with sample preparation
- Discussion of both chromatographic separation and mass spectrometric analysis
- Characterization of analytes in order to unequivocally identify banned substances
- Mass spectrometric behavior of low- and high-molecular weight analytes
Throughout the book, descriptive examples illustrate the principles, advantages, and limitations of different assays.
Mass Spectrometry in Sports Drug Testing
not only sets forth the role mass spectrometry plays in detecting drug
use among athletes, it also adds new insights into the health and
ethical issues of doping in sports.
