2nd Edition
by Igor A. Kaltashov (Author), Stephen J. Eyles (Author), Dominic M. Desiderio (Series Editor), Nico M. Nibbering (Series Editor)
The definitive guide to mass spectrometry techniques in biology and biophysics
The
use of mass spectrometry (MS) to study the architecture and dynamics of
proteins is increasingly common within the biophysical community, and
Mass Spectrometry in Structural Biology and Biophysics: Architecture,
Dynamics, and Interaction of Biomolecules, Second Edition provides
readers with detailed, systematic coverage of the current state of the
art.
Offering an unrivalled overview of modern MS-based
armamentarium that can be used to solve the most challenging problems in
biophysics, structural biology, and biopharmaceuticals, the book is a
practical guide to understanding the role of MS techniques in
biophysical research. Designed to meet the needs of both academic and
industrial researchers, it makes mass spectrometry accessible to
professionals in a range of fields, including biopharmaceuticals.
This
new edition has been significantly expanded and updated to include the
most recent experimental methodologies and techniques, MS applications
in biophysics and structural biology, methods for studying higher order
structure and dynamics of proteins, an examination of other biopolymers
and synthetic polymers, such as nucleic acids and oligosaccharides, and
much more.
Featuring high-quality illustrations that illuminate
the concepts described in the text, as well as extensive references that
enable the reader to pursue further study, Mass Spectrometry in
Structural Biology and Biophysics is an indispensable resource for
researchers and graduate students working in biophysics, structural
biology, protein chemistry, and related fields.