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Matrix Proteases in Health and Disease

Description

1st Edition

by Niels Behrendt (Editor)

Presenting a comprehensive overview of the multifaceted field of proteases in the extracellular matrix environment, this reference focuses on the recently elucidated functions of complex proteolytic systems in physiological and pathological tissue remodeling. The proteases treated include both serine proteases such as plasminogen activators and TTSPs, metalloproteases such as MMPs and ADAMS and cysteine protease cathepsins. The text specifically addresses the role of extracellular proteases in cancer cell invasion, stroke and infectious diseases, describing the basic biochemistry behind these disease states, as well as therapeutic strategies based on protease inhibition.

With its trans-disciplinary scope, this reference bridges the gap between fundamental research and biomedical and pharmaceutical application, making this required reading for basic and applied scientists in the molecular life sciences.

Details

Year:
2012
Pages:
404
Language:
English
Format:
PDF
Size:
2 MB
ISBN-10:
3527329919
ISBN-13:
978-3527329915
ASIN:
B00DF945SQ
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