1st Edition
by Simon C. F. Rawlinson (Editor)
An emerging field at the interface
of biology and engineering, mechanobiology explores the mechanisms by
which cells sense and respond to mechanical signals―and holds great
promise in one day unravelling the mysteries of cellular and
extracellular matrix mechanics to cure a broad range of diseases. Mechanobiology: Exploitation for Medical Benefit
presents a comprehensive overview of principles of mechanobiology,
highlighting the extent to which biological tissues are exposed to the
mechanical environment, demonstrating the importance of the mechanical
environment in living systems, and critically reviewing the latest
experimental procedures in this emerging field.
Featuring
contributions from several top experts in the field, chapters begin with
an introduction to fundamental mechanobiological principles; and then
proceed to explore the relationship of this extensive force in nature to
tissues of musculoskeletal systems, heart and lung vasculature, the
kidney glomerulus, and cutaneous tissues. Examples of some current
experimental models are presented conveying relevant aspects of
mechanobiology, highlighting emerging trends and promising avenues of
research in the development of innovative therapies.
Timely and important, Mechanobiology: Exploitation for Medical Benefit
offers illuminating insights into an emerging field that has the
potential to revolutionise our comprehension of appropriate cell biology
and the future of biomedical research.
