1st Edition
by Li-He Zhang (Editor), Zhen Xi (Editor), Jyoti Chattopadhyaya (Editor), Sidney M. Hecht (Foreword)
Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology
Assembling
contributions from a collection of authors with expertise in all areas
of nucleic acids, medicinal chemistry, and therapeutic applications, Medicinal Chemistry of Nucleic Acids
presents a thorough overview of nucleic acid chemistry―a rapidly
evolving and highly challenging discipline directly responsible for the
development of antiviral and antitumor drugs. This reliable resource
delves into a multitude of subject areas involving the study of nucleic
acids―such as the new advances in genome sequencing, and the processes
for creating RNA interference (RNAi) based drugs―to assist
pharmaceutical researchers in removing roadblocks that hinder their
ability to predict drug efficacy. Offering the latest cutting-edge
science in this growing field, Medicinal Chemistry of Nucleic Acids
includes:
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In-depth coverage of the development and application of modified nucleosides and nucleotides in medicinal chemistry
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A close look at a large range of current topics on nucleic acid chemistry and biology
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Essential information on the use of nucleic acid drugs to treat diseases like cancer
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A
thorough exploration of siRNA for RNAi and the regulation of microRNA,
non-coding RNA (ncRNA), a newly developing and exciting research area
Thorough in its approach and promising in its message, Medicinal Chemistry of Nucleic Acids
probes the new domains of pharmaceutical research―and exposes readers
to a wealth of new drug discovery opportunities emerging in the dynamic
field of nucleic acid chemistry.
