1st Edition
by Janine Cossy (Editor), Stellios Arseniyadis (Editor)
All the latest tools needed to plan and perform the synthesis of complex bioactive molecules
Focusing
on organic, organometallic, and bio-oriented processes, this book
explores the impact and use of the latest synthetic tools for the
synthesis of complex biologically active compounds. Readers will
discover step by step how these synthetic tools have provided new,
elegant solutions to many synthetic puzzles. Moreover, they will
discover innovative methods that make it possible to control the exact
connectivity of atoms within a molecule in order to set precise
three-dimensional arrangements.
Modern Tools for the Synthesis of Complex Bioactive Molecules
features sixteen chapters, each one written by one or more leading
experts in organic synthesis from around the world. It covers a broad
range of topics that enable readers to take advantage of the latest
methods for synthesizing complex molecules, including:
- Modern
catalysis, emphasizing key transformations such as C-H
functionalizations, cross-couplings, gold-catalyzed reactions,
metathesis-based syntheses, and asymmetric organocatalysis
- Eco-compatible transformations, including rearrangements and domino reactions
- Tools for the synthesis of carbohydrates and alkaloids
- New techniques, including the use of fluorous tags and engineered biosynthesis
The
last two chapters explore target- and diversity-oriented organic
synthesis as well as the use of DNA-based asymmetric catalysis, which
are all promising tools for the successful synthesis of complex
bioactive molecules.
Modern Tools for the Synthesis of Complex Bioactive Molecules
is ideal for students and researchers who need to plan and perform the
synthesis of complex molecules as efficiently as possible. The book's
expert advice will help these readers quickly resolve a broad range of
problems that can arise in organic syntheses.
