1st ed. 2019 Edition
by Sajal Chakraborti (Editor), Naranjan S. Dhalla (Editor), Madhu Dikshit (Editor), Nirmal K. Ganguly (Editor)
This book highlights the multifaceted roles of Reactive Oxygen
Species (ROS) in modulating normal cellular and molecular mechanisms
during the development of different types of heart disease. Each chapter
in the book deals with the role that altered redox homeostasis plays in
the pathophysiology of heart disease. In addition, the book explains
how reactive oxidant species interact with their targets and provides
novel strategies for attenuating oxidative stress-induced types of heart
disease.
The book not only covers ROS-induced response in heart
disease at the cellular level, but also demonstrates that an imbalance
of redox states has its roots in our genes, and explains the ways gene
expression is regulated. In turn, it reviews potential sources of ROS,
their pathological effects on the heart, and potential sites for
therapeutic interventions.
