English | 2023 | PDF | 21 MB | 484 Pages
Jitender Madan, Ashish Baldi, Monika Chaudhary, Neetu Chopra, 9780323916639, 978-0323916639, 978-0-323-91663-93, B0CB83GJRB, 0323916635, 0323916902, 9780323916905, 978-0323916905
Polymer-Drug Conjugates: Linker
Chemistry, Protocols and Applications discusses important concepts,
fundamentals and prospective applications of 'Linker Chemistry' in a
clear-and-concise manner. The book provides vital information on
chemical entities binding with the drug-polymer complex for targeted
drug delivery systems. It highlights roles and significance, different
classes and synthetic protocols as well as mechanisms of chemical bond
formation in drug-polymer conjugation in drug delivery, also offering
insights into the mechanism of polymer interaction with linker and drug
molecules by biodegradable chemical bonding.
The
protocol of binding with drug molecules is clearly explained and
justified with case studies, helping researchers and advanced students
in the pharmaceutical sciences understand fundamentals involved and
related aspects in molecule designing for effective therapeutic
benefits.
- Covers mechanism, protocol and therapeutic significance of Polymer-Drug Conjugates
- Outlines updated methods and techniques to enumerate conjugation with related case studies
- Includes comprehensive compilation of marketed and clinical trial drugs conjugated with polymers or linkers
