(Methods in Molecular Biology) 2014th Edition
by Laura Poliseno (Editor)
Providing a list of methods useful
both to those who wish to study pseudogenes and to those who actually
want to avoid their inadvertent detection, Pseudogenes: Functions and Protocols explores
techniques involving pseudogenic DNA, RNA, and peptides/proteins, once
believed to lack any functionality, but now known to be involved in
complex regulatory circuits. After a few introductory chapters that
overview the functions so far attributed to pseudogenes, this thorough
volume delves into methods for pseudogene identification, for the
detection of pseudogene transcription and translation, and for the study
of the functions of pseudogenic RNA and proteins, as well as methods to
avoid pseudogene detection when the focus of the research is their
highly homologous parental counterparts. As part of the highly
successful Methods in Molecular Biology series, chapters feature
the kind of detailed descriptions and implementation advice that ensures
successful results in the lab.
Authoritative and practical, Pseudogenes: Functions and Protocols
will contribute to the high interest of the scientific community toward
pseudogenes, while stimulating the conception of pseudogene - centered
research projects and providing experimental protocols that can
facilitate their execution.